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Microfluidic components
for life science

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Components for life science

PLANOPTIK develops and manufactures custo­mized microfluidic chips and microstructured components made of glass, quartz, silicon and glass-silicon combinations for life science applica­tions, including lab-on-chip, organ-on-chip and advanced cell-based microfluidic systems.

We support customers from feasibility assessment and proto­typing to repeatable series production, combining precision microstructuring, optical functionality and application-specific fluidic design.

Application fields:

– MEDICAL SOLUTIONS
– PHARMACEUTICAL APPLICATIONS
– DIAGNOSTICS
– BIOTECHNOLOGY
– ANALYTICAL APPLICATIONS
– LABORATORY APPLICATIONS

Logo LTF

Little Things Factory is a brand of PLANOPTIK.

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Microfluidic chips

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Microfluidic chips enable the precise transport, control and processing of very small liquid volumes within microchan­nels, chambers and functional structures. They form the technological basis for a wide range of applica­tions in life science, diag­nos­tics, biotechnology and pharmaceutical research.

PLANOPTIK develops and manufactures custo­mized microfluidic chips made of glass, quartz, silicon and glass-silicon combinations. Depending on the application, precisely defined micro­channels, cavities, through-holes, fluidic interfaces, optical areas and bonded multilayer structures can be integrated into the device.

We support customers from feasibility assessment and prototyping to repeatable series production.

Typical applications:

  • Sample preparation and analysis
  • Controlled fluid handling, mixing and reaction processes
  • Cell-based, diagnostic and analytical microfluidic systems

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Lab-on-chip

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Lab-on-chip technology integrates laboratory functions such as sample handling, mixing, reac­tion, separation or analysis into compact micro­fluidic devices. This can reduce sample and reagent consumption while enabling precisely controlled and reproducible analytical workflows.

Customized microfluidic components are made of glass, quartz and silicon with precisely defined channels, chambers, through-holes and fluidic interfaces. The high optical transparency and chemical resistance of these materials make them particularly suitable for demanding analy­tical, diagnostic and biological applications.

Typical applications:

  • Point-of-care and molecular diagnostics
  • Sample preparation and biochemical assays
  • Miniaturized analytical and laboratory systems
Lab-On-Chip

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Cell encapsulation

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Cell encapsulation uses microfluidic processes to enclose individual cells or defined cell populations within droplets, hydrogels or other controlled microenvironments. Precise and reproducible droplet generation enables highly controlled encapsulation processes and defined conditions for subsequent biological analysis or cultivation.

We manufacture precision microfluidic chips with customized channel geometries and junction designs for controlled droplet generation and encapsulation workflows. Flow-focusing, cross-flow and application-specific microfluidic structures can be adapted to the required flow conditions, droplet characteristics and process requirements.

Typical applications:

  • Single-cell encapsulation and analysis
  • Cell-loaded hydrogel and microgel generation
  • High-throughput biological screening and assays

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Droplet generation with microstructured glass chips

Flow-focusing and cross-flow geometries enable controlled and reproducible droplet generation for cell encapsulation and other microfluidic workflows.

Organ-on-chip

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Organ-on-chip

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Organ-on-chip platforms use controlled micro­fluidic environ­ments to reproduce selected physio­logical conditions for cell and tissue culture. Defined fluid flow, biochemical stimuli and controlled microenvironments can be used to create advanced in-vitro models for biomedical and pharmaceutical research.

PLANOPTIK develops and manufactures custo­mized micro­fluidic components for organ-on-chip platforms. Precisely de­fined microchannels and culture chambers can be com­bined with optical access, chemically resistant materials, fluidic inter­faces and bonded glass structures tailored to the individual device concept.

Typical applications:

  • Drug efficacy and toxicity screening
  • Disease modelling and personalized medicine research
  • Advanced in-vitro tissue and organ models
Organ-on-chip

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Typical applications:

  • Fluorescence and optical detection
  • Cell and particle sorting or positioning
  • Microscopy-based particle and cell characterization
Optofluidics

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Drug delivery

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Drug delivery technologies are designed to deliver phar­maceutical substances in a controlled, effi­cient and reproducible manner. Microstruc­tured components and precision nozzles can influence droplet size, spray charac­teristics, dosage and liquid distribution and therefore play an important role in advanced drug delivery systems.

PLANOPTIK’s micro nozzles are made of glass or glass-silicon combinations with customized geo­metries for pharmaceutical and medical applica­tions. Wafer-based microstructuring, bonding and dicing enable highly reproducible component geometries and scalable pro­duction from deve­lop­ment to series manufacturing.

Typical applications:

  • Soft-mist inhalers
  • Pharmaceutical aerosol and spray generation
  • Microneedle-based drug delivery systems

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How wafers are turned into microcomponents for soft mist inhalers

How wafers are turned into microcomponents for soft mist inhalers

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Wafer Microstructuring

Glass or glass-silicon wafers are processed with thousands of precisely defined micro­structures using application-specific microfabrication technologies.

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Wafer bonding

Structured wafers are aligned and permanently bonded to create the required functional micro­struc­tures and fluidic interfaces.

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Microcomponent after wafer dicing

The processed wafer stack is diced into individual precision micro­components.

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Integration into the final device

The finished microcomponents are integrated into the customer-specific drug delivery system.

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Key advantages of glass
in life science

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Advantages Plus

Low
Fluorescence

Advantages Plus

Bio
compatibel

Advantages Plus

Long term
stable

Advantages Plus

Optical
transparency

Advantages Plus

Chemical
resistance

Advantages Plus

Heat
resistance

Advantages Plus

High mixing
intensity

Advantages Plus

UV
transmission

Result

Cost
effective!

Result

No hurdles
when upscaling!

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Meet with PLANOPTIK

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Your personal advisor

Alexander Schilling
Markus Schneider

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Team up with PLANOPTIK

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Team up with PlanOptik
Team up with PlanOptik

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Individually developed

Are you developing a new microsystem? Are you combining microelectronics, micromecha­nics or microfluidics to create a new product? Are you developing a sensor, an electronic device, a fluidic system or something that has never existed before? Team up with PLANOPTIK.

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Reliable partnership

In us you will find a partner who will work with you to develop electronic, mechanical, optical, chemical or biological microcomponents and has a firm grasp of materials such as glass, silicon and copper.

Team up with PlanOptik

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Together until production

PLANOPTIK also manufactures the jointly deve­loped microcomponents and elements in high volumes using state-of-the-art wafer-based manufacturing processes.